All Episodes

February 3, 2016
ask-dr-mike-trouble-sleeping-on-supplements-arterial-plaqueHere you'll find the answers to a wealth of health and wellness questions posed by Healthy Talk fans.

Listen in because what you know helps ensure healthy choices you can live with. Today on Healthy Talk, you wanted to know:

I’ve been taking 100 mg of CoQ-10 enzyme for cell energy for many years. In the past six weeks, I’ve started taking AMPK activator as well. Lately I’ve had trouble sleeping more than four or five hours a night. I have lots of energy. I’m 72 and have a 70% raw food diet that I alternate with a paleo-ish diet two to four times per day. I've rarely had sugar for the past two years. I avoid most bread and eat grains and nuts. Is the high energy-low sleep because of the CoQ-10 and AMPK supplements?

AMPK activator contains ynostemma pentaphyllum and rose hip extract. Those have been shown to activate an enzyme in your cells called AMPK. When AMPK is activated in your cells, they manage energy better. You tend to make more ATP (coenzyme used as an energy carrier in the cells), burn more fat,and  burn more sugars. The cell becomes cleaner and functions at a higher level.

When people first start taking CoQ-10, they may feel energized and have some sleepless nights because their blood level of CoQ-10 was so low and it's being recharged. Your body will reach a steady state with a supplement and there will not be peaks and valleys. The energy you might get early from CoQ-10 is gone, but the supplement is still good for you. You should be at a steady state with it if you take it on a consistent basis.

The addition of the AMPK activator could be the culprit. It creates cell energy, which the CoQ-10 was already doing. You may reach a steady state with the AMPK activator in another week. If nothing changes after a week, try dosing every other day or every third day. If that doesn’t help, stop the AMPK activator and just use the CoQ-10.

My question is about plaque in the blood. As we try to eat healthy and supplement to clean our blood, is there a chance that a dissolved or dislodged piece of plaque might float around and cause blockage down the line?

Eating better, getting more exercise, taking supplements targeted to the cardiovascular system and supplements targeted to the plaque itself (pycnogenol made from pine bark extract, pomegranate, vitamin K2, gotu kola, EDTA, resveratrol) can help with plaque burden. Nothing totally gets rid of plaque. It's more about stabilizing the plaque.

You can decrease plaque burden by doing the right things. The body puts a fibrous cap on the plaque, shrinking the plaque and decreasing the plaque burden. You’ve stabilized the plaque and it is less prone to rupture. Your body knows how to take care of the plaque. The contents of the plaque (fat, cholesterol, immune cells) can be absorbed by the arterial wall itself or just leave as you stabilize the plaque. Vitamin K2 can help the cap become stronger and keeps calcium out of the way. Focus on stabilizing the plaque to prevent cardio events in the future.

If you have a health question or concern, Dr. Mike encourages you to write him at askdrmikesmith@radiomd.com or call in, toll-free, to the LIVE radio show (1.844.305.7800) so he can provide you with support and helpful advice.
Mark as Played

Advertise With Us

Popular Podcasts

On Purpose with Jay Shetty

On Purpose with Jay Shetty

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

Ruthie's Table 4

Ruthie's Table 4

For more than 30 years The River Cafe in London, has been the home-from-home of artists, architects, designers, actors, collectors, writers, activists, and politicians. Michael Caine, Glenn Close, JJ Abrams, Steve McQueen, Victoria and David Beckham, and Lily Allen, are just some of the people who love to call The River Cafe home. On River Cafe Table 4, Rogers sits down with her customers—who have become friends—to talk about food memories. Table 4 explores how food impacts every aspect of our lives. “Foods is politics, food is cultural, food is how you express love, food is about your heritage, it defines who you and who you want to be,” says Rogers. Each week, Rogers invites her guest to reminisce about family suppers and first dates, what they cook, how they eat when performing, the restaurants they choose, and what food they seek when they need comfort. And to punctuate each episode of Table 4, guests such as Ralph Fiennes, Emily Blunt, and Alfonso Cuarón, read their favourite recipe from one of the best-selling River Cafe cookbooks. Table 4 itself, is situated near The River Cafe’s open kitchen, close to the bright pink wood-fired oven and next to the glossy yellow pass, where Ruthie oversees the restaurant. You are invited to take a seat at this intimate table and join the conversation. For more information, recipes, and ingredients, go to https://shoptherivercafe.co.uk/ Web: https://rivercafe.co.uk/ Instagram: www.instagram.com/therivercafelondon/ Facebook: https://en-gb.facebook.com/therivercafelondon/ For more podcasts from iHeartRadio, visit the iheartradio app, apple podcasts, or wherever you listen to your favorite shows. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

The Joe Rogan Experience

The Joe Rogan Experience

The official podcast of comedian Joe Rogan.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.