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December 14, 2025 20 mins
As Director of The Men's Clinic at UCLA, Dr. Jesse Mills has spent his career helping men understand their bodies, their hormones, and their health. Now he's bringing that expertise to The Male Room - a podcast where data-driven medicine meets common sense. Each episode separates fact from hype, science from snake oil, and gives men the tools to live longer, stronger, and happier lives. With candor, humor, and real-world experience from the exam room and the operating room, Dr. Mills breaks down the latest health headlines, dissects trends, and explains what actually works - and what doesn't. Smart, straightforward, and entertaining, The Male Room is the show that helps men take charge of their health without the jargon.Episodes available here:Https://www.iheart.com/podcast/1119-the-male-room-with-dr-jes-306117711/ 

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Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
I first arrived inside this forest in November of nineteen
ninety two, and right away I had to know what
is the history of this lay of land, what happened
here and how did it happen? What was the foresight
of what was about to take place? The arrival of humans?
Four stories on arrow dot Net A R. R Oe
dot Net. Enjoy the exploration. Let's bring it, man, dude,

(00:23):
I'm telling you you've got an idea here that I
think is going to become such a moment. But I
think it's going to be more than just men. They're
going to check in. I think women searching for their
husband's answers are going to check in as well. I mean,
you you really have opened up what, like my mother
would say, a can of worms here.

Speaker 2 (00:40):
I'm hoping for. Yeah, that's right.

Speaker 3 (00:42):
I mean the tagline is it's a podcast for men
and the people that love them.

Speaker 2 (00:45):
So that's right.

Speaker 3 (00:47):
We let everybody in and and you know, just to
back it up with data, about seventy percent of healthcare
decisions in a traditional family are made by the woman.
So that means that you, guys very rarely are taking
care of their own health. They're looking to their wives,
to get things done, and not just for their kids,
but for them too. I mean, I will tell you

(01:07):
when I when I see my clinic in the morning
and I see what the guy's there for you. I
can't tell you how often it's an appointment schedule by wife,
appointment schedule by.

Speaker 2 (01:15):
Wife, and it goes down the list.

Speaker 3 (01:17):
So the guy's not gonna go into the doctor unless
his wife is saying, bro, you gotta go do this.

Speaker 1 (01:23):
Well, dude, it doesn't matter where you go Starbucks, to
a grocery store, to a bank. It's when the guy
looks up at his wife and all they have to
do is share a look. You know they're talking about. Yeah,
go make the call to your doctor. I mean, because
it's there, it's in the look, it's in the body language.

Speaker 2 (01:38):
That's right. Well, that's right.

Speaker 3 (01:39):
And again, a lot of the things I deal with
as a urologist and a specialist, infertility is and sexual
medicine are two things you can't hide from your partner.
If you have a problem with your sperm counts and
you're trying to make a baby and it doesn't happen,
you need to see a doctor. The other thing is
we always say in medicine. You know, you can hide
chest pain from your wife, but you cannot hide erect
out as function from her. She's gonna know eventually that

(01:59):
things not working down there.

Speaker 1 (02:01):
She looks up at me right now. My wife just
looked up at me. It's like, oh, crap, I just
got busted by the doctor.

Speaker 2 (02:09):
Well, there you go.

Speaker 1 (02:11):
She's just looking out for you.

Speaker 3 (02:12):
Roh.

Speaker 2 (02:12):
Let me come on, this is what we're here for.
There's that.

Speaker 3 (02:15):
Don't think that you know, single, single guys die a
lot sooner than married guys, and single women live a
lot longer than married women.

Speaker 2 (02:23):
So what does that tell you? We just were those leeches.

Speaker 3 (02:26):
The parasites said that glom onto our women at short
in their lives and lengthen ours. And yeah, we got
to reverse that narrative. We got to we gotta start
pulling our weight.

Speaker 1 (02:36):
One of the things that I find so interesting on
your podcast is the fact that when you invite people
in even with yourself, when you when you're doing just
a regular one on one, you're so down to earth.
It's not like that, hey, I'm a radio guy trying
to do this talk like this. What happens is is
that you're so real you're going, you know what, here's
a situation we you know, let's talk about this today.

Speaker 2 (02:55):
That's right.

Speaker 3 (02:56):
Yeah, I got a voice for TV. You should see
my face, but I don't have that radio.

Speaker 2 (03:00):
You got that? Yeah, I mean, I think that's the goal.

Speaker 3 (03:02):
I'm a professor of urology, so you know, I've got
all of the sheepskin on the wall to say that
I'm smart, But it doesn't do a guy much good
if you can't really speak with them. And I think
that's my goal with this podcast, is that I can
see a few thousand guys a year in my clinic,
have a very very busy surgical and medical practice. But boy,

(03:23):
there's so many other men that need to hear this voice,
that need to get this information out there, and the
only way to do it is an easily digestible form,
not in a two hour long session where we're really
diving into the weeds.

Speaker 2 (03:34):
We need actionable items.

Speaker 3 (03:36):
We need a guy to listen for a half hour,
forty five minutes and say what am I going to
do today that I didn't do yesterday because of what
I heard on doctor Mills's podcast.

Speaker 2 (03:44):
That's the goal, that's what it's all about.

Speaker 1 (03:45):
Ero see, I know a bunch of eighteen to thirty
year old men that need to be listening to this
podcast because they all say, oh, I don't care if
I'm meeting bad now. I said, it's going to catch
up to you when you're forty. Trust me, it's going
to catch up. And they're not listening to me. But yet,
I know at forty seven and I had my heart
attack and doctor Fandetti said, well, what did you do
back in your twenties.

Speaker 2 (04:04):
Dude, Yeah, yeah, no, it's true.

Speaker 3 (04:08):
I mean, you know, I got two boys in that
demographic twenty and twenty seven, and both of them are
giving me the thumbs up. They're they're shipping it out
to all their friends, so that so that demographic does learn,
because you're right. The thing about us as guys is,
our wives were married, they get to see.

Speaker 2 (04:24):
Their guyd of collegers.

Speaker 3 (04:25):
When they're eighteen, they get they start getting screened for
cervical cancer, they start talking about oral contraception. They have
that indoctrination. You and I we turn the left and
cough in our high school physicals. We can go play
football and we're done until forty forty five, and you're
a perfect example, I didn't thank you for sharing your
story with me, Hero because I didn't know that.

Speaker 2 (04:44):
But you're right. You know.

Speaker 3 (04:46):
We should get our blood checker, blood pressure checked, we
should be getting our heart recheck. We should be getting
questions are you wearing your seatbelt? Are you wearing a
helmet where you're on wheeled, wheeled vehicles? All those things
that we don't do. By the time we get to
forty we could be our already in trouble. By time
we get to forty five, that's when we start screening
for colon cancer, we could already have early disease that
could have been picked up in our twenties and thirties.

(05:08):
That's what I'm here for because as a urologist isn't
a sexual health specialist. If a guy has problems with
his sexual health, his fertility, He's going to see me
and I'll be able to figure out if he has
a cardiovascual issue or not by doing the work up
on his sexual dysfunction. That's the beauty of what I
do is that I get to meet guys where they're at,
take care of what they want to be seen for,

(05:29):
but also take care of them holistically.

Speaker 2 (05:31):
At the same time.

Speaker 1 (05:32):
Oh my god, you bring up such a very interesting
point in the way that guy will try. The average
guy will bulk it up and make it look like
he's the manly man goes to the doctor, and that
doctor will know in seconds that he's putting on a facade.

Speaker 3 (05:46):
Yep, that's right. Yeah, that's a beautiful thing. I mean,
when that door closes in my exam room, it's just
me and him trying to figure this out. And that's
where guys, they do have to give me just a
little bit of vulnerability and that then we can we
can get off and face the world together and you
can put up that stoic front again. But but yeah,
we gotta, we gotta, we gotta break down that wall.

(06:08):
Get him in the office, get him on the air,
listen to the podcast, so you can know when it's
time to see a doc and get the carry you need.
So that's right, so that you you don't have to
go through what you went through at forty seven.

Speaker 1 (06:19):
Now is the doctor supposed to be the cheerleader. And
I'm gonna bring up an example here and you can
put me in my place, please, And that is is
that the doctor for two years kept saying lose the weight.
Lose the weight, lose the weight, get those get that
heart right, you know, rate down. Give me. It's the
only way you're gonna get. Lose the weight. And then
when I do and I go in there, he didn't
pat me on the back. He said it could be
something else. We're gonna have to watch it. Come back

(06:39):
in six months and we're gonna do your numbers again,
and I'm going I lost the weight for you, dude.

Speaker 3 (06:45):
Ah, yeah, Well you bring up really good point. I
mean when I talk with my guys, I say, look,
I I spent six years learning how to operate.

Speaker 2 (06:54):
I'm a surgeon.

Speaker 3 (06:55):
I spent time in the ICU and trauma and all
of this stuff to be the surgeon. But my goal
is not to operate on you. My goal is to
start off as your coach. My goal is to be
your coach for the twenty minutes, the thirty minutes an
hour that you're in my office. In a year, you
got three hundred and sixty four days and twenty three
hours to do that for yourself, to take care of

(07:17):
your own self with my coaching. The nice thing about
being a doc is that I also can help them
if I think they would benefit from a prescription, from
a surgery, from some kind of physical therapy, whatever it is.
A nutritionist, I can put together that team. I can
assemble the dream team for that guy to optimize his
health as long as he's willing to put in the

(07:37):
reps when he's not in my office. So that's what
it's all about. It is definitely a team and coaching mentality.

Speaker 1 (07:45):
I'm probably very wrong here, but I'm a firm believer
that a lot of male problems is not necessarily their ego,
but their gut. They need more pro bionics. They need
something to take care of that gut because it's controlling
the energy of every place else in the body.

Speaker 2 (08:02):
Right. Yeah.

Speaker 3 (08:02):
I mean the idea of the microbiome, which is all
the bacteria that live within us in areas that we
didn't even know they lived in before, is essential to
overall health.

Speaker 2 (08:14):
It's that heema homeostasis.

Speaker 3 (08:17):
Rather with your environment, and our microbiome will change based
on where we are, based on our latitude, based on
our longitude, based on and I think in this country,
one of the things that we know is that we
overprescribe antibiotics. And when you give a guy an antibiotic
for an air infection, for a sinus infection. You're not
just killing the bad players, which we have to kill,

(08:38):
but you're killing all of the good guys as well.
And how do those get repleated. Well, there's probably a
role for probiotics in there. There's also a role for
eating probiotics, not necessarily as a capsule or a supplement, but.

Speaker 2 (08:49):
Eating them as part of your overall food.

Speaker 3 (08:52):
And if you look at cultures across the world, they
all have probiotics, from sauerkraut to kimchi. Yes, these are
all things that cultures have developed that are integral into it.
And why is that Because because if you're fermenting something
on your counter, those good bacterior out there fighting the

(09:12):
battle against the bad bacteria, and they're trying to get
into your gut to set up a defense right to
protect you and to protect your gut lining protect your colon.
You know, it is not quite the right format, but
I'll give you a twenty second. Thing we did here
in fertility is that we actually looked at the microbiome
in the male reproductive tract and we found that guys

(09:32):
that have fertility problems, even if they're sperm counts normal.
They have some bad players in their reproductive tract. Looking
at their sequencing of bacteria, and when we looked at
fertile guys, they had a fully different, very healthy microbiome
within their semen, within their reproductive track. So even on
a fertility level, it's not just about your gut era.

(09:54):
It's about every part of our body should have a
healthy microbiome. It should have healthy She's a bacteria that
keep the bad guys out and when that breaks down,
that's when we get in trouble.

Speaker 1 (10:06):
Please do not move. There's more with doctor Jesse Mills
coming up next, the name of his podcast, The mail Room.
We are back with doctor Jesse Mills. Do you think
we're taking too many supplements? Because my wife was looking
at the stuff I was taking today and she says,
how many heart meds are you taking? I said, I'm not.
I know, I'm not. There's only like four things I'm

(10:27):
taking every day. But you should see the long list
of supplements I'm doing.

Speaker 3 (10:31):
Dude. Yeah, well, I mean you know the answer is,
I don't know. I mean I think that there are
some supplements that are very well vetted. I will tell
you in my field el citraline. You know, the amino
acid is incredibly important for nitric oxide metabolism, which is
really good for cardiovascer health, it's great for penile and
sexual health.

Speaker 2 (10:51):
That's been studied.

Speaker 3 (10:52):
They're good randomized controlled trials showing that el citriline works.
So I think you just want to know where that
supplement is coming from. And then they're always the hot ones,
like burberine is the hot one. Now why because it's
kind of like a very weak GLP like your ozepis,
your manjarros. Berberine has that effect, but you got to

(11:12):
take it in such a high concentration. I got to
ask yourself, well, should I be doing that or should
we seeing a doctor to get a prescription for something
that has better data. So in general the answer is
probably you might be taken too many. But if you
were doing this, and I think that's what I always
challenge is if you're hitting your fundamentals, if your nutrition
is excellent, you're eating a good whole foods diet without

(11:35):
any ultra process food or limiting the amount of simple
sugar you intake.

Speaker 2 (11:39):
If you're exercising to the.

Speaker 3 (11:41):
Point where you're in what we call that zone, two
metabolic rate, where your heart rates, you know, based on
your age, a little bit above the point where you
can have a long winded conversation. You're doing that and
you're sleeping at least six to seven hours a night. Eat, move, sleep,
then let's talk supplements, but don't come to me until
your fundamentals are strong. Then we'll go up to that

(12:02):
next level and then we'll say, okay, well, here's where
we can fill in the gaps. Here's the little mortar
repair we're going to do to your brick house. That
is your body with supplements. Same thing with protein. I
think you know we eat a lot of protein, some
guys probably overdoing it. Protein is in everything these days.
But if you're working out, if you're training, then you
probably need that extra protein. But if you're just clicking

(12:24):
on it because it's on your internet feed and you're
not getting off the couch and getting off your laptop,
you know, do that first and then start talking protein,
start talking supplements.

Speaker 1 (12:33):
All right. Here is where I'm guilty. And your podcast
is called The mail Room, which is on iHeartRadio and
every other format. The thing is is that I'm that
guy that was taking all of these things like ibuprofit
and advil and to leave. And I was using it
as a preventative and not a painkiller. Oh my god,
that is so wrong, so wrong.

Speaker 3 (12:57):
Yeah, yeah, yeah, No, I mean I think it's interesting.
I mean those are anti inflammatories as a class. They're
called nonsteroidal anti inflammatory drugs or NSAIDs. Well, you know,
so it turns out that inflammation is actually not bad.
We hear all the time, Oh, everything's into you, gotta

(13:17):
app be inflaming more. Inflammation is terrible, it's bad for everything.
But our body's inflammatory mechanism is what fights off disease.
It's what helps us repair joints. So the worst thing
that I can do, and I'll tell you me personally,
I've been training for a marathon with my younger son
and putting in miles and I'm fifty five years old
and you know I'm not thirty anymore. And the worst

(13:38):
thing I could do is if I went on a
long run where my joints are sore and I'm feeling it,
That's when I want inflammation. That's when I want my
body to heal all those muscles and my joints that
I just pounded twenty miles with and if I take
an ibuprofen, if I take an asp in any of
those things, I'm actually inhibiting that natural, good inflammatory response.

Speaker 2 (13:58):
So instead of.

Speaker 3 (13:59):
Taking a hot shower, may be very very very little
exposure to ice, because too much ice actually is also
not good for your recovery. Those are the kind of
things you could do naturally as well as just rest,
give yourself some time, and you're absolutely stay away from
the ibuprofen. The only time that I think ibuprofen or
any of those medicines works is when I'm operating on

(14:19):
somebody and I'm doing a surgery where I want them
to have really good pain control without giving them narcotics.
Then we will use an IV form of those medications,
just one shot in the oar, and that dramatically reduces
their post up pain, improves their recovery. But after that, nope, nope,
I want them to stay away from that stuff. So

(14:39):
let me ask you kind of a personal question, because
you're bringing up an interesting point about being in that
operating room, and right away, in my mind, I'm thinking,
this man knows the outside of who we are, but
when he gets in that operating room, all of a
sudden he can't judge the book by its cover because
he's inside what's going on?

Speaker 2 (14:59):
Yeah, yep, yeah, no.

Speaker 3 (15:01):
I mean that's one of the most amazing and sacred
aspects of what I do in my job as a
physician and as a surgeon, is that men are trusting
their lives to me, literally and trusting their outcomes to me.
And I never take that lightly. And you're right, you
know how you look on the outside. When I get
in there and try to fix something, it may be
an entirely different story, you know.

Speaker 2 (15:22):
And I'm in La, I'm in Santa Monica.

Speaker 3 (15:25):
I mean, every guy that I see who's eighty two
years old looks like they're forty, right. I Mean, we
got perfect faces, we got no wrinkles left. But yet
if you're not taking care of those insides, it's going
to come out in the oar. And there's a big
difference between eighty year old guy and a twenty five
year old guy when I'm operating. But I will tell
you this that you can make your insides better if

(15:46):
you're following the principles of longevity, healthy heating, excellent exercise.

Speaker 2 (15:51):
Then we're talking.

Speaker 3 (15:52):
Then you can actually reverse some of that aging process
and make your body look more like that beautiful face
of yours.

Speaker 1 (15:58):
You are speaking one hundred percent the truth and why.
And that's exactly why people need to go to the
mailroom on your podcast, because you're because before my heart attack,
I was studying for my third degree black belt in
martial arts. I really felt like I was doing fantastic.
And the thing is, I got a pain in my
throat on the right side. I thought it was strep throat. Dude,
I was having a heart attack. Yeah, man, yeah, no,

(16:23):
I mean that's it. You're right, is that you you
can do everything right now. I will tell you this,
first of all, congratulations on that level of discipline to
do what you're doing. I mean, that's next level arrow.
But you can do that.

Speaker 3 (16:34):
And maybe you made it to forty seven when if
you hadn't been as good as shape, okay, you may
have had that problem when you're thirty eight, I say,
thirty eight year old guys that have these problems. So
the bottom line is you gotta get screened. You gotta
see ducks to make sure your blood pressures okay, make
sure your cholesterol levels are okay.

Speaker 2 (16:49):
That's just the media. The middle. Right, that's and then
if you go above that, we can bring in things.

Speaker 3 (16:54):
Like calcium scoring to make sure that you don't have
any early athers clerosis. Then yeah, you're really getting it
to the weeds. But yeah, God bless you for recognize it.
Was it you or is it your wife that told
you to go to the ar at that point?

Speaker 2 (17:06):
Lee?

Speaker 1 (17:06):
Who was it? I just did a four hour lecture
up at a university and coming down the mountain, I
wanted to do a red bull, but I felt like
that that's not a good idea. I had no clue.
But can you imagine if I would have done that
red bull knowing that I was having a heart attack?

Speaker 2 (17:21):
Yeah? Boom, yeah, immediate vase of constriction.

Speaker 1 (17:24):
Wow.

Speaker 2 (17:24):
Wow Right.

Speaker 1 (17:25):
So what is it about you Bruins being from UCLA?
Because my daughter is a graduate from UCLA. And the
way that you guys tackled the reality of life is
that you understand it and you share it. You don't
preach it, you don't sit there and belittle somebody. You
share different things. What is it about the Bruins?

Speaker 2 (17:43):
Yeah?

Speaker 3 (17:44):
I think it's a West Coast mentality. If we try
to be friendly, most of us West Coasters started off
like me. I went to medical school at Iowa, so
I've got good Midwestern roots and we come out here
the sunshine, the beautiful nature of what we do. But
ultimately we practice really high level medicine. We try to
make it accessible.

Speaker 2 (18:02):
You know, I don't. I don't.

Speaker 3 (18:03):
I don't practice in an ivy tower. I meet guys
where they're at. But I'm in a lab. You know,
we have a full research laboratory where we're looking at
things like I just was talking about with my the
seminal microbiome story we have and and if you don't
make it relatable, then then you're not.

Speaker 2 (18:19):
Going to make it translatable.

Speaker 3 (18:20):
And you have to be able to translate what we
do in the lab, what we do in science to
make sure people are getting the information they need. And
and that's that's that's how we do it. And yeah,
I'm I'm honored, and I've been a Bruin since nineteen
eighty nine. I went to undergraduate here and basically just
kept on plugging away, just kept on plugging away. I started, ironically,

(18:40):
I started in the mail room, the m AI l
room as a putting myself through college as a freshman
here and now I'm hosting the mail Room m al E.
So my spelling got worse, but I think my medicine
got better.

Speaker 1 (18:53):
So are you? Are you like me?

Speaker 3 (18:54):
Though?

Speaker 1 (18:54):
That when when you're when you're going throughout your day
knowing that you've got a podcast in the future, does
it have to be the one that's this week, could
be one for seven or eight weeks from now, and
then you go, oh, that would make a good subject
for a podcast. Let me go ahead and put that down.
I'm gonna do you do it too?

Speaker 2 (19:08):
Oh all the time?

Speaker 3 (19:09):
So I you know, I have a producer on air
with me, Jordan Unta, who's fantastic, and I will just
text him.

Speaker 2 (19:14):
I mean, the poor guy.

Speaker 3 (19:15):
He's in Brooklyn and I'm in LA and is nine
thirty at night last night, and I came up with
his idea. I said, Jordan, we got to do this.
And I thought, oh my wait, I can't do this
to this poor guy. But he's you know, he's a
music guy. So he was up at twelve thirty saying, yeah,
I'm going to put fresh eyes on this in the morning,
which is basically like Mills. You realize it's twelve thirty
at night in Brooklyn, right now, right, but yes, all
the time. I mean, the beautiful thing is that I

(19:36):
can't sit still, so I still have a very full
time job. You know, I got a full list of
patients I'm going to see in clinic. I got a
full day in the or tomorrow on Wednesday. But when
I'm not doing that, I'm thinking about what I can
do to get the message out to treat more guys,
because there's only one to me, and I can only
see so many guys in a year. But so many
people need this good basic information. So many people need

(19:58):
to separate the fact the fiction. And let's have some
fun doing it.

Speaker 2 (20:02):
You know.

Speaker 3 (20:03):
I like to say serious medicine, serious fun. And I
think if we if we learn a lot and laugh
a little, then then we're doing it right.

Speaker 2 (20:09):
Wow.

Speaker 1 (20:10):
Please come back to this show anytime in the future.
The door is always going to be open for you.

Speaker 2 (20:15):
Arah.

Speaker 3 (20:15):
I appreciate it. I mean, this has just been great
and I love you sharing your story. I mean that
just right there, what you just said, I guarantee you
saved lives just by sharing that one aspect of your
history and being vulnerable. There are gonna be guys out
there are thinking, yeah, you know what.

Speaker 2 (20:29):
This doesn't quite feel right.

Speaker 3 (20:31):
I'm you know, I'm in great shape too, but but yeah,
my arm's starting to tingle or you know whatever. So
I appreciate what you're doing, and you keep it, Keep
staying strong, keep staying fit. We're gonna rage, rage as
long as we can in this beautiful world of ours.

Speaker 1 (20:46):
Be brilliant today, okay sir?

Speaker 2 (20:48):
Hell yeah, all right er, be well
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Crime Junkie

Crime Junkie

Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by Audiochuck Media Company.

The Brothers Ortiz

The Brothers Ortiz

The Brothers Ortiz is the story of two brothers–both successful, but in very different ways. Gabe Ortiz becomes a third-highest ranking officer in all of Texas while his younger brother Larry climbs the ranks in Puro Tango Blast, a notorious Texas Prison gang. Gabe doesn’t know all the details of his brother’s nefarious dealings, and he’s made a point not to ask, to protect their relationship. But when Larry is murdered during a home invasion in a rented beach house, Gabe has no choice but to look into what happened that night. To solve Larry’s murder, Gabe, and the whole Ortiz family, must ask each other tough questions.

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