Let's start with what's working. Ozempic continues to demonstrate significant effectiveness for weight loss, producing mean weight reduction of fourteen point nine to seventeen point four percent over sixty eight weeks in people without diabetes. The higher dose formulation, known as Wegovy, shows even more impressive results, with studies consistently showing greater average weight loss compared to the lower doses found in Ozempic. For millions managing type two diabetes or seeking weight management solutions, these medications have become game changers.
But here's what listeners need to know right now. Recent research is raising important safety concerns that demand our attention. A June 2025 study published in JAMA Ophthalmology found that patients taking semaglutide were twice as likely to develop neovascular age related macular degeneration, a condition that gradually destroys central vision. While the absolute risk remains small, researchers from the University of Toronto identified this link as statistically significant. The mechanism makes sense too. Semaglutide alters vascular and inflammatory pathways directly implicated in macular degeneration.
The vision concerns aren't the only ones. A January 2025 study in JAMA Otolaryngology found that patients initiating Glucagon like Peptide One receptor agonist therapy had a significantly increased risk of thyroid cancer diagnosis within the first year of use compared to other diabetes medications. Researchers analyzed data from over three hundred fifty thousand adults with type two diabetes.
Then there's gastroparesis, the stomach paralysis condition that's become central to ongoing litigation. Multiple lawsuits allege that Novo Nordisk, the manufacturer, failed to provide adequate warnings about this risk. The lawsuits argue the company knew or should have known about the potential link based on clinical studies and medical literature. Patients reported persistent vomiting, nausea, and extreme stomach discomfort after starting the medication.
The legal landscape shifted in December 2024 when the Judicial Panel on Multidistrict Litigation ruled to expand the Glucagon like Peptide One receptor agonist lawsuit to include claims involving Saxenda, though blood clot related injuries were excluded due to complexity concerns.
What does this mean for you? If you're considering Ozempic or Wegovy, talk to your doctor about these emerging risks alongside the proven benefits. If you're already taking these medications and experiencing vision changes, thyroid issues, or stomach problems, document everything and consult your healthcare provider.
The story of Ozempic isn't finished. As evidence emerges, companies face questions not just about what they disclosed but about what they should have investigated. The scientific community continues watching as more data arrives.
Thank you so much for tuning in to Ozempic Weightloss Unlocked. Please subscribe to stay updated on the latest developments in semaglutide research and safety updates. This has been a Quiet Please production. For more, check out Quiet Please dot ai.
Some great Deals https://amzn.to/49SJ3Qs
For more check out http://www.quietplease.ai
This content was created in partnership and with the help of Artificial Intelligence AI
Episode Transcript
Welcome to ozepic weight Loss Unlocked, the podcast where we
break down the latest developments in semaglutide medications and what
they mean for your health. I'm your host, and today
we're diving into the most important updates from twenty twenty five.
Let's start with what's working. Ozepic continues to demonstrate significant
effectiveness for weight loss, producing mean weight reduction of fourteen
(00:23):
point nine to seventeen point four percent over sixty eight
weeks in people without diabetes. The higher dose formulation, known
as WEGOVI shows even more impressive results, with studies consistently
showing greater average weight loss compared to the lower doses
found in ozempic. For millions managing type two diabetes or
(00:43):
seeking weight management solutions, these medications have become game changes.
But here's what listeners need to know right now. Recent
research is raising important safety concerns that demand our attention.
A June twenty twenty five study published in Jamma Ophthalmology
found that patients taking summer glutide were twice as likely
(01:06):
to develop neovascular age related macular degeneration, a condition that
gradually destroys central vision, while the absolute risk remained small.
Researchers from the University of Toronto identified this link as
statistically significant. Semaglutide alters vascular and inflammatory pathways directly implicated
(01:27):
in macular degeneration. The vision concerns aren't the only ones.
A January twenty twenty five study in jama Ottolaryngology found
that patients initiating glucoggin like peptide IE receptor agonist therapy
had a significantly increased risk of thyroid cancer diagnosis within
(01:49):
the first year of use compared to other diabetes medications.
Researchers analyzed data from over three hundred and fifty thousand
adults with type two diabetes. Then there's gas tarisis the
stomach paralysis condition that's become central to ongoing litigation. Multiple
lawsuits alleged that Novo Nordisk, the manufacturer, failed to provide
(02:10):
adequate warnings about this risk. The lawsuits argue the company
knew or should have known about the potential link based
on clinical studies and medical literature. Patients reported persistent vomiting, nausea,
and extreme stomach discomfort after starting the medication. The legal
landscape shifted in December twenty twenty four when the Judicial
(02:30):
Panel on Multidistrict Litigation ruled to expand the glucagon like
peptide one receptor agonist lawsuit to include claims involving sexender,
though blood clot related injuries were excluded due to complexity concerns.
What does this mean for you? If you're considering ozempic
or WEGAV, talk to your doctor about these emerging risks
(02:52):
alongside the proven benefits. If you're already taking these medications
and experiencing vision changes, viroid issues, or stomach problems, document
everything and consult your healthcare provider. The story of ozempic
isn't finished. As evidence emerges, companies face questions not just
about what they disclosed, but about what they should have investigated.
(03:17):
The scientific community continues watching as more data arrives. Thank
you so much for tuning in to ozempic Weight Loss Unlocked.
Please subscribe to stay updated on the latest developments in
semaglutide research and safety updates. This has been a quiet
(03:38):
please production. For more check out quiet Please dot ai
Popular Podcasts
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
Ruthie's Table 4
For more than 30 years The River Cafe in London, has been the home-from-home of artists, architects, designers, actors, collectors, writers, activists, and politicians. Michael Caine, Glenn Close, JJ Abrams, Steve McQueen, Victoria and David Beckham, and Lily Allen, are just some of the people who love to call The River Cafe home. On River Cafe Table 4, Rogers sits down with her customers—who have become friends—to talk about food memories. Table 4 explores how food impacts every aspect of our lives. “Foods is politics, food is cultural, food is how you express love, food is about your heritage, it defines who you and who you want to be,” says Rogers. Each week, Rogers invites her guest to reminisce about family suppers and first dates, what they cook, how they eat when performing, the restaurants they choose, and what food they seek when they need comfort. And to punctuate each episode of Table 4, guests such as Ralph Fiennes, Emily Blunt, and Alfonso Cuarón, read their favourite recipe from one of the best-selling River Cafe cookbooks. Table 4 itself, is situated near The River Cafe’s open kitchen, close to the bright pink wood-fired oven and next to the glossy yellow pass, where Ruthie oversees the restaurant. You are invited to take a seat at this intimate table and join the conversation. For more information, recipes, and ingredients, go to https://shoptherivercafe.co.uk/ Web: https://rivercafe.co.uk/ Instagram: www.instagram.com/therivercafelondon/ Facebook: https://en-gb.facebook.com/therivercafelondon/ For more podcasts from iHeartRadio, visit the iheartradio app, apple podcasts, or wherever you listen to your favorite shows. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com
The Joe Rogan Experience
The official podcast of comedian Joe Rogan.