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July 29, 2025 76 mins

#862. Katie Thurston is back on the pod with her husband, comedian Jeff Arcuri, and this one’s equal parts emotional and hilarious. We get all the real updates—where she’s at with stage 4 cancer, what the treatment looks like day-to-day, and how she’s become a major voice for advocating earlier mammograms and pushing doctors to listen.

Katie opens up about the stat that most men leave after a diagnosis—and how Jeff did the opposite and married her. We also talk about their IVF journey, the grief of not being able to carry a child, and how Katie continues to encourage Jeff to chase his comedy career—even in the middle of everything. 

You’ll hear how they met, how humor plays a role in the darkest moments, and why laughter and love are getting them through it. There are tears, there are laughs, and at the end of the day—it’s just a feel-good episode with friends. Enjoy!

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EPISODE HIGHLIGHTS: 

  • (11:20) — Katie’s stage 4 cancer updates and tumor shrinkage
  • (23:47)— Jeff’s comedy world tour update!
  • (40:30) — How Katie and Jeff met!
  • (50:00) — IVF journey: hopes, grief, and what’s ahead!


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