Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you've come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.

Episodes

October 26, 2026 • 77 mins

When we think of computers, we think of machines running on some kind of silicon chips. But the idea is more general: at heart, a computer is any object that takes in input, processes information, and produces output. Taking inspiration from biology, it is interesting to imagine building computers out of DNA -- a molecule that can store and process information, and is even programmable. Erik Winfree is one of the leading scientists...

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Humanity is merely one s...

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October 12, 2026 • 211 mins

Welcome to the October 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a si...

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One reason it's been so hard to directly detect the dark matter is that we're not sure what it is. But for a long tim...

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The worry about debates ...

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In all sorts of ways, th...

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Welcome to the September...

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The course of history is...

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Everyone lives through t...

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Black holes, as Stephen ...

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One of the paradoxes of ...

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Large Language Models display an uncanny ability ...

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Welcome to the August 2026 Ask Me Anything episod...

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People who live in large cities produce more pate...

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One of the characteristics of life is that living...

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Welcome to the July 2026 Ask Me Anything episode ...

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Modern life has, in many ways, removed us from th...

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June 29, 2026 • 116 mins

The cosmological constant, as discussed last episode, provides a perfectly good (thus far) explanation for why we observe the universe to be accelerating. But it might not be the right explanation, and demonstrating that would be yet another foundational discovery. In this episode I discuss what is required to invent a plausible theory of dynamical dark energy, This includes considerations from particle physics, possible exper...

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The most surprising discovery in fundamental physics during my career as a scientist was undoubtedly the acceleration of the universe, announced in 1998. The most straightforward explanation for these observations is a positive cosmological constant, or vacuum energy. I talk about the origin of the idea with Einstein, how quantum physicists started to think about it and understand the "cosmological constant problem," as well a...

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Messenger RNA (mRNA) plays a literally central ro...

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