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December 31, 2025 58 mins

Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal?

In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes.

Inflammation isn't just a body problem.
It's a brain health issue first.

Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.

🧠 What You'll Learn in This Episode

✔ Why fatigue often begins as brain fatigue and inflammation
✔ How inflammation changes perception, memory, and focus
✔ Why stress and unresolved trauma amplify inflammation
✔ The connection between blood sugar instability and brain fog
✔ How hormonal changes increase inflammation and cravings
✔ Why circulation and oxygen delivery are critical for healing
✔ How peptides may support inflammation regulation and mitochondrial health
✔ Why labs miss inflammation — but patterns don't
✔ How a personalized, holistic approach is the future of health


🚨 Signs of Brain Inflammation (Even When Labs Look "Normal")

  • Brain fog after meals

  • Morning stiffness lasting longer than 30 minutes

  • Energy crashes or "wired but tired" feeling

  • Poor recovery from exercise

  • Mood and cognition fluctuations

  • Low HRV or elevated resting heart rate

  • Elevated CGM readings or blood sugar swings

Pattern recognition often detects inflammation long before labs do.


⏳ Why Inflammation Makes You Feel "Old"

When inflammation stays elevated:

  • Cells don't repair efficiently

  • Mitochondria produce less energy (ATP)

  • Hormone signaling becomes disrupted

  • Blood sugar regulation worsens

  • Fat storage increases

  • The brain becomes less efficient

That's why so many people say:

"I feel inflamed, puffy, foggy, and exhausted — but nothing is technically wrong."


🔄 The Key Reframe

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