Today’s show discussed approaches for modeling absorption profiles. I discussed the rationale behind modeling absorption and then described some common models. These included first-order absorption, zero-order absorption, transit compartments, distributed delay, Weibull, and zero/first order absorption. I also provided my recommendations on how to model absorption.
Links discussed in the show:
- Distributed delay modeling in PK and PD
- Modeling biphasic formulation of methylphenidate
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