All Episodes

October 14, 2022 18 mins

Understanding another layer of the DIGIN model to potential root causes of chronic disease- intestinal permeability.

 This episode discusses:

  • gut barrier function
  • factors that influence intestinal permeability that may lead to chronic inflammation and disease - IBD, leaky gut, and more
  • current assessment and testing techniques, including specific biomarkers
  • how we can regulate the gut barrier with diet, prebiotics, and probiotics
  • proposed dietary factors/interventions to support the gut barrier 


  • Camilleri M. (2019). Leaky gut: mechanisms, measurement and clinical implications in humans. Gut, 68(8), 1516–1526.
  • Yu, S., Sun, Y., Shao, X., Zhou, Y., Yu, Y., Kuai, X., & Zhou, C. (2022). Leaky Gut in IBD: Intestinal Barrier-Gut Microbiota Interaction. Journal of microbiology and biotechnology, 32(7), 825–834.
  • Schoultz, I., & Keita, Å. V. (2020). The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability. Cells, 9(8), 1909.
  • Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J. D., Serino, M., Tilg, H., Watson, A., & Wells, J. M. (2014). Intestinal permeability--a new target for disease prevention and therapy. BMC gastroenterology, 14, 189.
Mark as Played

Advertise With Us

Popular Podcasts

Dateline NBC
Crime Junkie

Crime Junkie

If you can never get enough true crime... Congratulations, you’ve found your people.



In order to tell the story of a crime, you have to turn back time. Every season, Investigative journalist Delia D'Ambra digs deep into a mind-bending mystery with the hopes of reigniting interest in a decades old homicide case.

For You

    Music, radio and podcasts, all free. Listen online or download the iHeart App.


    © 2023 iHeartMedia, Inc.