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August 20, 2025 63 mins

 Short Summary:
Women may live longer—but they spend more of those years in poor health. In this essential conversation, Piraye Beim, MD & founder of Celmatix, reveals why ovarian aging is the hidden accelerant of female biological decline—and why extending ovarian healthspan could be the next major breakthrough in longevity science. From inflammaging to AMH biomarkers, Dr. Beim brings cutting-edge reproductive science into the center of the longevity discourse.

This episode also features insights from Beth McGroarty, VP of Research & Forecasting at the Global Wellness Institute.  

Inside this episode:

  • The “gonadal gap”: why menopause accelerates aging for women
  • Why ovarian function is a key regulator of brain, bone, and metabolic health
  • How tracking AMH levels could transform preventive care for women in their 30s and 40s
  • The underfunding of female longevity research—and how that’s starting to change
  • ARPA-H and other public-private partnerships funding therapeutic innovations
  • The potential to delay menopause and extend healthspan through new medical approaches

Resources Mentioned:


Hosted by: Alexia Brue, co-founder of Well+Good; founder of a new healthspan training studio, The Practice; member of the Global Wellness Institute Board of Advisors

To learn more about the Global Wellness Institute please visit us at global wellness institute.org, connect with us on Instagram and subscribe to our YouTube channel. 

Produced by: Emily Roberts and Ali Alquiza of Over Lunch 

Music provided by: Myndstream    

Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com to learn more.

Subscribe, rate, & review wherever you listen to podcasts! 



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