The following is a conversation with Dr Saman Maleki, associate professor at Western University with a special focus on oncology, immuno oncology, microbiology, and everything to do with the immune system and the microbiome.
Dr Maleki is a pioneer and a world leader in the field of sensitising tumours to immunotherapy through modulating the microbiome.
During this conversation, we talked about the state of the art associated with the microbiome and cancer. So if you're interested in how cancer impacts the microbiome and how the microbiome impacts cancer you should listen to this episode. We delved into what the latest evidence is for the use of FMT in making a particular type of cancer therapy called immunotherapy better for treating particular cancers.
We talked about the journey from doing the first trials to the area where they are now, which is raising funds to do much larger trials that should definitively prove that changing the microbiome can massively improve response rates to cancer therapies.
Even as someone who's got their finger on the pulse of this field, I left the conversation enthusiastic and excited about the potential in the future for developing efficient microbiome treatments to tackle cancer.
00:00:00 Introduction
00:01:38 First interest in the microbiome
00:05:46 FMT for C-Diff patients
00:09:11 Using the immune system to treat cancer
00:19:03 Microbiome research for oncology
00:23:46 Journey from first study
00:27:30 Stimulating immune system with FMT
00:39:09 Chemotherapy, pancreatic cancer and the microbiome
00:48:29 Novel cell therapy and chemotherapy
00:49:02 Future of immunotherapy
00:52:32 Immune therapy response in cancer treatment
00:55:41 Antibiotics and cancer treatment
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